Gli1 Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comGli1 Polyclonal Antibody for Mouse(Mus musculus)

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Gli1 (Gene name),

Zinc finger protein GLI1 (Protein name ), GLI1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gli1(Gli);

Protein name:

Zinc finger protein GLI1;

Alternative:

Glioma-associated oncogene homolog;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with ZIC1; the interaction enhances transcription activation (By similarity). Interacts with KIF7.

Function:

Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

Subcellular Location:

Cytoplasm Nucleus Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.

Protein Attributes:

Sequence length:

1111

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

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550:

600:

650:

700:

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950:

1000:

1050:

1100:

1111:

PGETQFLNSS | A

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P47806

STRING:

10090.ENSMUSP00000026474

Pfam:

PF00096

SMR:

P47806

KEGG:

mmu:14632

UniGene:

Mm.391450

Uniprot:

P47806

FOR

ELISA Kit for Mouse Zinc finger protein GLI1

Cat.:

E15198m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Zinc finger protein GLI1

Cat.:

E15198h

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Zinc finger protein GLI1

Cat.:

E15198c

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Zinc finger protein GLI1

Cat.:

U15198m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Zinc finger protein GLI1

Cat.:

U15198c

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Zinc finger protein GLI1

Cat.:

U15198h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Zinc finger protein GLI1

Cat.:

P15198Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Zinc finger protein GLI1

Cat.:

P15198Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Zinc finger protein GLI1

Protein for Mouse Zinc finger protein GLI1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of the promoter region and genomic organization of GLI, a member of the Sonic hedgehog-Patched signaling pathway."
Liu C.Z. , Yang J.T. , Yoon J.W. , Walterhouse D. , Iannaccone P.
Gene209:1-11(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling."
Sasaki H. , Nishizaki Y. , Hui C. , Nakafuku M. , Kondoh H.
Development126:3915-3924(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: ICR.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development."
Waterhouse D. , Ahmed M. , Slusarski D. , Kalamaras J. , Boucher D. , Holmgren R. , Iannaccone P.
Dev. Dyn.196:91-102(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 272-837
strain: CD-1.
tissue: Embryo.
6.

"The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development."
Endoh-Yamagami S. , Evangelista M. , Wilson D. , Wen X. , Theunissen J.W. , Phamluong K. , Davis M. , Scales S.J. , Solloway M.J. , de Sauvage F.J. , Peterson A.S.
Curr. Biol.19:1320-1326(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KIF7

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